General Cell Lines and Cell Cultures
ATCC Bacillus sp.; Strain: E601
Bacillus sp. strain E601 is a whole-genome sequence bacterium with applications as an ionizing radiation-sterilization control. This strain is recommended by ATCC for use in the tests described in U.S. Pharmacopeia where only the taxon is specified.
Eurofins Discoverx InCELL Hunter U2OS Bcl2-Bim Protein Binding Cell Line, 2 vials. (96-0008C3)
The InCELL Hunter U2OS Bcl2-Bim Protein Binding Cell Line provides an easy-to-use cell based assay to study small molecule drug candidates that disrupt protein binding. This kit assesses compound-based disruption of Bcl2-Bim binding via detection of Bim levels. This product uses EFC technology. The cell line included overexpresses Bcl2 target in an untagged form and Bim binding partner fused to ProLabel. When a compound engages the Bcl2 target protein, partner binding is disrupted and the destabilized Bim is degraded, leading to a loss of EFC signal upon addition of EA containing detection reagent. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Discovery Life Sciences Lung Cancer Tx Naive PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
Eurofins Discoverx Ready-to-Assay α1A Adrenergic Receptor Frozen Cells, 2 Vials of Cells. (HTS087RTA)
The Ready-to-Assay α1A Adrenergic Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. epinephrine and norepinephrine) based activation of ADRA1A GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses ADRA1A alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of ADRA1A, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx ChemiScreen S1P3 Lysophospholipid Receptor Stable Cell Line, 2 vials. (HTS097C)
The ChemiScreen S1P3 Lysophospholipid Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. S1P) based activation of S1PR3 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses S1PR3 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of S1PR3, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen OX1 Orexin Receptor Stable Cell Line, 2 vials. (HTS175C)
The ChemiScreen OX1 Orexin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. orexins) based activation of HCRTR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses HCRTR1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of HCRTR1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Quantified DNA from; Clostridium perfringens; Strain 26; with ATCC 16S Tag 2
Quantitative genomic DNA from Clostridium perfringens with ATCC 16S Tag 2 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load. The synthetic Tag 2 allows for use as a spike-in control in assay development, library preparation, quality control, and data normalization for both 16S rRNA and shotgun metagenomics approaches. This product is also a component of ATCC MSA-1014.
Cayman Chemical H2S Donor 5a, Purity: ≥98%, CAS: 134861-13-5, 10 mg
A stable, cysteine-activated H2S donor
ATCC Escherichia coli; 6 x 0.3mL
Escherichia coli strain AMC 198 (ATCC 11229-MINI-PACK) consists of 6 ready-to-use vials of ATCC 11229 frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping. This product has a variety of applications including testing membrane filters, absorbant pads, antimicrobial handwashing formulations, disinfectants, ink grids, and sanitizers.
Eurofins Discoverx PrecisION hKv12.2 Recombinant Stable Cell Line, 2 vials. (CYL3089)
The PrecisION hKv12.2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Kv12.2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Kv12.2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
ATCC Bilophila wadsworthia
Bilophila wadsworthia strain WAL 7959 [Lab 88-130H] is a whole-genome sequenced bacterial type strain that was isolated from a perforated appendiceal abscess. This organism is a strict anaerobe.
ATCC Escherichia coli
Escherichia coli strain Crooks was isolated from feces. This certified reference material can be used in testing and calibration in ISO 17025-accredited laboratories to challenge assay performance, validate or compare test methods, and establish sensitivity, linearity, and specificity during assay validation or implementation.
Cell Applications Inc Cryopreserved Rat Dorsal Root Ganglion Neurons (RDRGN)
Cryopreserved Rat Dorsal Root Ganglion Neurons (RDRGN)
Cell Applications Inc Proliferating Bovine Renal Artery Endothelial Cells (BBMVEC)
Proliferating Bovine Renal Artery Endothelial Cells (BBMVEC)